Alternatively Activated Macrophages in Types 1 and 2 Diabetes
نویسندگان
چکیده
منابع مشابه
Alternatively Activated Macrophages in Types 1 and 2 Diabetes
Macrophages are innate immune cells derived from monocytes, which, in turn, arise from myeloid precursor cells in the bone marrow. Macrophages have many important roles in the innate and adaptive immune response, as well as in tissue homeostasis. Two major populations have been defined: The classically activated macrophages that respond to intracellular pathogens by secreting proinflammatory cy...
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Macrophages not only initiate and modulate immune responses, but also are the final effector cells. Recent studies suggested that macrophages conventionally associated with IFN-gamma dominant Th1-type responses and also playing an essential role in the Th2-type inflammatory response, exhibit a quite different activation from the classically activated macrophages (CAM Phi) stimulated during Th1-...
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ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 2012
ISSN: 0962-9351,1466-1861
DOI: 10.1155/2012/815953